Stress Management Effects on Health What Is Toxic Stress? By Julie Nguyen Julie Nguyen Julie Nguyen is a certified relationship coach and freelance mental health and sexuality writer. Her writing explores themes around mental well-being, culture, psychology, trauma, and human intimacy. Learn about our editorial process Updated on October 15, 2022 Reviewed Verywell Mind articles are reviewed by mental health professionals. Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Steven Gans, MD Reviewed by Steven Gans, MD Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Learn about our Review Board Print LaylaBird / Getty Images Table of Contents View All Table of Contents Healthy Stress When Does Stress Become 'Toxic'? Signs & Symptoms Stress' Impact on Your Brain How Stress Affects Children Stress-Relief Tips Can the Effects of Toxic Stress Be Reversed? Trending Videos Close this video player Stress is a biological response to external or internal pressures. If the stressors are severe and persistent, stress can be considered toxic. Healthy Stress Can Be Good for You Stress is a universal occurrence and a normal experience. It can be positive or negative. A 2015 study from the University of California, Berkeley found how acute levels of optimal stress, known as eustress, can benefit individuals and optimize alertness, behavioral, and cognitive performance to adapt to situations better. When Does Stress Become 'Toxic'? In the face of stress, the body responds by releasing hormones and neurotransmitters causing the physiological changes necessary for the fight and flight response. The individual’s heart rate and blood pressure increase, muscles tense and respiration increases to face the perceived danger. Once the stressor has been confronted, the stress response then deactivates and returns the body back to a balanced and relaxed bodily state. Too Many Stressors Leads to Toxic Stress If exposure to the stress becomes chronic or overwhelming, the body shifts into an ongoing stress response. Without an off switch to the stressor, the internal alarm bells remain activated—even after the threat is long and gone. The Build-Up of Stress & Your Health In the face of toxic stress, chronically elevated cortisol and other physiologic and brain changes increase the risk of cardiovascular, infectious, inflammatory, metabolic and psychiatric disorders. In other words, as your stress continues to increase, your physical and mental health begins to decline. Signs of Toxic Stress Learning to identify how toxic stresscan affect one's physicality, behaviors, and emotions is the first step to reducing its health risks. There are common symptoms that can be a reflection of chronic stress, including but not limited to: Headache Muscle tension Fatigue Upset stomach Sleep disturbances Restlessness Lack of motivation Chronic pain Feelings of overwhelm Irritability or anger Anxiety, sadness, or depression Substance abuse Social withdrawal How Prolonged Stress Impacts Your Health How Toxic Stress Affects Your Brain The brain is the command center for the human nervous system and appraises the threat level of a stressor. At healthy levels of stress, it can apply the appropriate behavioral and physiological responses. However, once stress builds up, it impacts the capacity of the brain to respond to stress, and even impacts the functioning of the brain itself. Your Brains Can Shrink Chronic stress has been found to actually decrease brain volume, causing loss of synapses and impacting brain functions. Your Critical Thinking Becomes Impaired The prefrontal cortex,located at the front of the frontal lobe of the brain, is particularly susceptible to stress exposure. This region of the brain is involved in our higher-order cognitive functions. Toxic stress can cause architectural changes in prefrontal nerve cells resulting in loss of certain cognitive abilities. Toxic Stress' Impacts Your Overall Neurobiology & Physical Health To understand its full impact, it may be helpful to consider a few different examples of how toxic stress can negatively impact one’s neurobiology. Heightened cortisol response which puts you at risk for increased heart problems, high blood pressure, digestive problems, weight gain, and more.Impaired mental health. Toxic stress can play a part in the pathophysiology of mental illnesses such as anxiety and depressive disorders, behavioral dysregulation, PTSD, and psychosis .Maladaptive changes to brain architecture. The physiological changes that accompany toxic stress can cause structural changes in the brain leading to problems such as memory and learning impairment. Modified gene expression. Toxic stress can change which genes are turned on or off, leading to a wide range of health consequences.Poor stress management and coping skills which inhibits one’s ability to manage challenging situations appropriately.Unhealthy lifestyles. Toxic stress nat lead to unhealthy lifestyle choices, which may contribute to a variety of health consequences including depression, cancer, or heart disease. Maintaining the brain’s health so it can respond to stress properly is vital to your well-being. How Toxic Stress Impacts Children Toxic stress is overwhelming for individuals of all age groups, but it is particularly damaging for children. Adverse Childhood Experiences and Stress As a child’s brain develops, adverse childhood experiences can alter the architecture in the brain, leading to impaired coping skills and debilitating long-term health effects. Without the proper emotional support from caretakers, toxic stress can create abnormal stress responses that might not reveal themselves for years. According to the Centers for Disease Control and Prevention (CDC), adverse childhood experiences can put one at risk for future violence victimization and mental illnesses. An ACE (adverse childhood experience) score is a tally of various abuse, neglect, and other hallmarks of a rough childhood—the higher the score, the higher the risk for health issues. The experiences that can contribute to toxic stress are events such as: Early life adversity Extreme poverty Household dysfunction Poor health Food scarcity Loss of a parent or a painful divorce Witnessing violence in the home or community Having a family member attempt or die by suicide Childhood abuse (emotional/physical/sexual) Childhood neglect Caretakers with substance problems or mental health conditions Ongoing exposure to less severe, yet chronic, daily stressors Instability due to parental separation or household members being in jail or prison Tips to Relieve Stress When you're feeling overwhelmed, take a moment to pause and reach for a healthy coping response that will serve your body and mind. Some possible techniques can look like this: Registering your physical body reactions when you're stressed, noticing if your breath constricts, your jaw tenses up, or your heartbeat races so you can take the steps to relax sooner rather than later Processing emotions, thoughts, and sensations as they come up—no matter how painful, frustrating, or intense they may feel Eating and drinking your meals with presence, putting down your phone and eating your food slowly while enjoying the sensation of the wind or the sun on your skin Safeguarding your sleep habits, proper sleep hygiene can help with memory retention, and learning ability, regulate your metabolism, and grow dendrites which are branches in brain cells that convey information from one neuron to the next Physical health improvement with exercise and movement Mindfulness and mind-body practices like yoga Doing these activities every day can help you promote and nurture a low-stress lifestyle. The brain is plastic and has some ability to rewire itself back to healthy functioning, For neuroplasticity to occur, the brain needs to be optimally stressed. How to Reverse the Effects of Toxic Stress Although stress can induce neural changes in the brain, the brain is remarkably resilient and can often bounce back from stress. Toxic stress can be a factor in a person’s life, but one can take steps to reverse its impact with several stress management techniques: Talk therapy with a trusted mental health professional Deep breathing or breath-work meditation to center yourself in the present moment Body scanning techniques Reflection through journaling or art Support from loved ones, friends, and family Developing and maintaining healthy relationships Mitigating stressful tasks with organization, to-do lists, and asking others for help Learning how to manage your response to toxic stress appropriately can help you tackle stress in the moment, and be better able to find balance and deal with stress when it emerges in the future. A Word From Verywell Building healthy and sustainable habits and practices to manage stress can allow you to get ahead of toxic stress and reduce its harmful effects. 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